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Not to be confused with Paint Shop Pro, which is a professional image-editing package available from Corel.

Photoshop is more than just an image-editing program. It also includes the following:

Advanced tools to manipulate and enhance your image: The standard brushes (found on the Brush panel) contain all the standard image-editing tools that you find on image-editing programs that don’t come with Photoshop. You can also use the Painting and Selection tools and follow all the standard image-editing procedures for modifying images.

The Layers palette, which enables you to organize and manipulate your image easily. Layers enable you to open an image and create multiple layers on top of each other for adding effects or altering images.

The Save and Export feature: You can create and save a single or multiple-layer image and save it in various formats for reading and manipulation by other software. This feature is useful for creating sophisticated, custom-designed publications.

The Draw tools: Photoshop offers a range of tools that enable you to draw directly on the canvas, adjusting the way lines, shapes, and color are set.

You can download the latest version of Photoshop from Adobe at www.adobe.com/products/photoshop or you can download older versions on the Adobe download site at www.adobe.com/products/photoshop/older.html. The latest version is CS3, but you can download the previous version of Photoshop as well.

Using the Photoshop interface

Photoshop is a complicated application with a lot of menu options. You need to spend some time getting familiar with the interface, and although it can be very daunting at first, the learning curve is very manageable.

I start with Photoshop in the standard view (see Figure 10-1), which displays the Toolbox panel on the left side of the image window. The following sections briefly describe each of the tools.

**Figure 10-1:** The basic tools in Photoshop.

Tool Options: This section enables you to tweak options for your current tool or switch to the next tool on the Tool Options menu (refer to Figure 10-1). If the tool is set to Default, the options are set to your default settings.

Delete: I recommend that you use this tool sparingly. When you use the Delete tool, you cannot revert to your previous tool.

Alignment/Distortion: This tool allows you to flip, rotate,

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Get the premium version of Photoshop Elements

Photoshop Elements was released in 2013 and there have been over 30 new updates since.

With little advertising, you are likely to find it on your computer without the trial period at no cost. There is no need to download and install anything else, it simply opens in a browser window.

Here is a quick overview of Photoshop Elements.

Part One. The Tools of the Trade.

The five tools of the trade. Getting started

Launching Photoshop Elements

The main menu interface

If you are trying to learn to use Elements, I suggest opening Photoshop Elements for the first time.

Creating a New File

There are four windows in the main menu that you will need to open first when starting with Photoshop Elements. The first two are in the same location on both Windows and Mac OS X. You will need to open the first two windows in order to create a file for your first image.

The third window is where you will find all of the important settings that you will have to adjust for your images. Finally, the fourth window will show you all of the images that you have created or inserted into your canvas.

Some of the elements in the main menu window

Getting Started by Importing Images

The important thing to remember is that you only need to import one image into Photoshop Elements to begin your editing. You will see it as a thumbnail on the right side of the main menu.

Over time, as you create new files, Elements will display them in the fourth window in the main menu (viewed horizontally on a Mac).

Add a new image

While you are in the main menu, you will see two small buttons (faces) at the bottom right. Clicking on one will give you the option to add an image, a template, or both.

Add a new image

For this tutorial, I will add a new image to our photo album.

Photoshop Elements automatically places your files in the following location if you press the green plus (add) button. You can also look for the folder in the file dialog window or navigate to it yourself.

Alternatively, you can choose a folder, or create a new one, within this location.

After your new file is created, you are presented with a thumbnail of your new file.

If you are familiar with Photoshop, you will notice that
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Effect of intravenous immunoglobulin (IVIG) on contact hypersensitivity induced by oxazolone in BALB/c mice.
Oxazolone, a hapten belonging to the contact allergen series, is used to investigate allergic contact dermatitis in vivo in mice. The antigen is administered in a single subcutaneous injection, since the severity of the skin reaction is maximal at this site. However, it is not a convenient injection method. In this study, we attempted to establish a new experimental model of antigen-specific contact hypersensitivity (CHS) using intravenously administered antigen in mice. CHS was induced by intravenous injection of antigen in BALB/c mice. The mice were subcutaneously sensitized with 3% oxazolone and challenged with 3% oxazolone 24 hr later. The magnitude of the skin reaction was maximal at 24 hr after the challenge, and was measured as a pixel count by subtracting the number of pixels where reaction was induced from the number of pixels where reaction was induced plus the number of pixels where no reaction was observed. The various sensitizing drugs were prepared in saline and administered intravenously (total volume of 5 ml) to mice. The mice were then sensitized with 3% oxazolone (7.6 mg/ml) in saline (5 ml), 0.02% chlorohexidine (5 ml), and 5% alum (0.1 ml) and then challenged with 3% oxazolone 24 hr later. Five micrograms of ovalbumin in 0.01 M phosphate-buffered saline (PBS) was also administered intravenously to examine its influence on oxazolone CHS. When 20 or 40 mg of the immunoglobulin fraction from B cell leukemic (B-CLL) of a patient with CHS was administered intravenously, the skin reaction was reduced in half. However, the skin reaction was increased when 5 micrograms of the ovalbumin fraction was administered intravenously. In contrast, when 20 or 40 mg of the immunoglobulin fraction from normal human serum (NHS) was administered intravenously, a complete inhibition of oxazolone CHS was observed. The potency of the inhibitory effect in NHS was higher than that in B-CLL. The sensitizing drugs and antigen administered intravenously did not affect the skin reactions to oxazolone when administered in a single subcutaneous sensitization.Q:

System Requirements:

Minimum:
OS: Windows XP SP2 or later (32 or 64 bit)
Processor: Intel Pentium 4 or AMD Athlon™ 64 processor
Memory: 1024 MB of RAM
Graphics: DirectX® 9 compliant video card
DirectX®: 9.0c
Hard Disk Space: 10 MB available hard disk space for installation
Recommended:
OS: Windows Vista SP2 (32 or 64 bit)
Processor: Intel Core™ 2 Duo or AMD Athlon™ 64 X2 processor
Memory: