Bs 6093 Pdf Free [CRACKED] 58
Bs 6093 Pdf Free 58
6093 Free download as PDF File (.pdf), Text File (.txt) or read. permitted without license from IHS Not for Resale, 12/26/2004 06:58:20 MST BSÂ . 7. C.S..
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33. C. S.. 6093 BS. 1.81. 2.53. 18.Heat exposure induces oxidative stress and free radical production in the synovial fluid of an arthritic animal model.
There is increasing evidence that oxidative stress may be involved in the pathogenesis of rheumatoid arthritis. We hypothesized that synovial fluid (SF) of an arthritic animal model would have increased oxidative stress compared to controls. Female Sprague-Dawley rats were injected with collagen II in Freund’s complete adjuvant (CA) or saline, followed by intra-articular injection of CA or saline once a week for a period of 5 weeks. During week 9, hind paws were heat challenged for 45 minutes at 42 degrees C by immersion of each hind paw in a 120 degrees C water bath. Rats were sacrificed by cervical dislocation 48 hours postheat exposure. Synovial fluid was collected from affected and unaffected knees. Oxidative stress in SF was assessed by measuring total anti-oxidant potential and the levels of free radicals. Heat-challenged CA SF samples had higher level of anti-oxidant capacity compared to control SF (p=0.031). The mean level of superoxide free radical was significantly higher (p=0.02) in heat challenged CA SF (12.9+/-4.8 pmol) compared to control SF (1.8+/-1.3 pmol). However, the levels of other free radicals and hydrogen peroxide were not significantly different between these two groups. These data showed that heat challenge induced oxidative stress in an arthritic animal model.Only a few hours left to Double your gift
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